New approaches to measurement and treatment research to improve cognition in schizophrenia.
نویسندگان
چکیده
An overview is provided of the set of articles included in this special issue of Schizophrenia Bulletin that were derived from the final meeting of the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) program. These essays summarize the presentations and discussions of the MATRICS New Approaches Conference that examined the future needs of the field for a coordinated research effort to improve the preclinical and clinical science required to optimize new cotreatments for the cognitive deficits in patients with schizophrenia. Specific priorities for a research agenda involving collaborations among academic, industrial, and governmental participants are addressed.
منابع مشابه
Social cognition in schizophrenia: recommendations from the measurement and treatment research to improve cognition in schizophrenia new approaches conference.
This article summarizes the discussion from a breakout group at the National Institute of Mental Health-Measurement and Treatment Research to Improve Cognition in Schizophrenia New Approaches Conference on social cognition in schizophrenia. During this discussion, the reasons for the recent growth of research on social cognition in schizophrenia were examined. The discussion group established c...
متن کاملDistinguishing separable domains of cognition in human and animal studies: what separations are optimal for targeting interventions? A summary of recommendations from breakout group 2 at the measurement and treatment research to improve cognition in schizophrenia new approaches conference.
At the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) New Approaches Conference, a discussion group focused on directions for future research that are critical to enhancing our understanding of the distinctions among key cognitive domains that have relevance for the development of cognition-enhancing interventions. One set of recommendations emphasizes the ne...
متن کاملDeveloping predictive animal models and establishing a preclinical trials network for assessing treatment effects on cognition in schizophrenia.
Animal models are an essential initial phase in the discovery of novel drugs to treat psychiatric disorders. At the sixth Measurement and Treatment Research to Improve Cognition in Schizophrenia conference, "New Approaches to Assessing and Improving Cognition in Schizophrenia," a discussion group was formed to address issues related to the development of predictive animal models of cognition th...
متن کاملNew paradigms for treatment development.
Wayne Fenton believed that government-particularly National Institute of Mental Health (NIMH)-could play a critical role in addressing important public health problems where the current system of treatment development was inadequate. Earlier experiences in HIV/AIDS convinced him and others that the NIMH can effectively facilitate the rapid development of new research in critical areas. This rep...
متن کاملFunctional neuroimaging and electrophysiology biomarkers for clinical trials for cognition in schizophrenia.
"Measurement and Treatment Research to Improve Cognition in Schizophrenia" or MATRICS is a National Institute of Mental Health (NIMH)--sponsored research effort to drive novel drug development for the treatment of cognitive impairments in schizophrenia. On September 9-10, 2004, MATRICS convened representatives from NIMH, academia, and industry for the final of a series of consensus-oriented con...
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عنوان ژورنال:
- Schizophrenia bulletin
دوره 31 4 شماره
صفحات -
تاریخ انتشار 2005